Peptides for muscle and growth hormone
Growth hormone releasers and related compounds: peptides that prompt the pituitary to release growth hormone, plus growth hormone itself and IGF-1 analogs. A few have approved uses; most are research compounds.
For education and research only. Not medical advice, and not a recommendation to use anything.
CJC-1295 (no DAC) + IpamorelinStack of two synthetic peptides (29 and 5 amino acids)
CJC-1295 with DACSynthetic GHRH analog with an albumin-binding linker
GHRP-6Synthetic peptide, 6 amino acids
Human growth hormone (HGH)Protein hormone, 191 amino acids
IGF-1 DESShortened form of IGF-1, 67 amino acids
IGF-1 LR3Modified IGF-1, 83 amino acids (a small protein)
MK-677 (ibutamoren)Small molecule (not a peptide), growth hormone secretagogue
PEG-MGFSynthetic peptide based on an IGF-1 variant, with PEG attached
SermorelinSynthetic peptide, 29 amino acids
Sermorelin + IpamorelinStack of two synthetic peptides (29 and 5 amino acids)
TesamorelinSynthetic peptide, 44 amino acids (modified GHRH)
Tesamorelin + IpamorelinStack of two synthetic peptides (44 and 5 amino acids)Side by side
What each one is and how much research is behind it.
| Name | What it is | Evidence so far | |
|---|---|---|---|
| CJC-1295 | Stack of two synthetic peptides (29 and 5 amino acids) | Mostly mechanism and animal data; no trials of the combination | Dosage |
| CJC-1295 with DAC | Synthetic GHRH analog with an albumin-binding linker | Small early human studies; no long-term outcome trials | Dosage |
| GHRP-6 | Synthetic peptide, 6 amino acids | Human hormone studies; other effects mostly in animals | Dosage |
| Human growth hormone | Protein hormone, 191 amino acids | Strong for deficiency; modest and mixed in healthy adults | Dosage |
| IGF-1 DES | Shortened form of IGF-1, 67 amino acids | Cell and animal studies only; no human trials | Dosage |
| IGF-1 LR3 | Modified IGF-1, 83 amino acids (a small protein) | Cell and animal studies only; no human trials | Dosage |
| MK-677 | Small molecule (not a peptide), growth hormone secretagogue | Several small human trials with mixed results | Dosage |
| PEG-MGF | Synthetic peptide based on an IGF-1 variant, with PEG attached | Cell and animal studies, mixed; no human trials | Dosage |
| Sermorelin | Synthetic peptide, 29 amino acids | Human data in children; small, older studies in adults | Dosage |
| Sermorelin + Ipamorelin | Stack of two synthetic peptides (29 and 5 amino acids) | Limited human data for each part; none for the combination | Dosage |
| Tesamorelin | Synthetic peptide, 44 amino acids (modified GHRH) | Large trials in people with HIV; small studies elsewhere | Dosage |
| Tesamorelin + Ipamorelin | Stack of two synthetic peptides (44 and 5 amino acids) | Large trials for tesamorelin; little for ipamorelin; none combined | Dosage |
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